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Figure 2
Verapamil, like
nifedipine, caused a concentration-dependent decrease in APD50
and APD90. Unlike nifedipine, however, verapamil also decreased
MRD by 69.4 ⮳%. In the case of verapamil, block of both the inward
calcium current and of sodium current may contribute to shortening of the
action potential.
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